Review of Holarrhena antidysenterica (L.) Wall. ex A. DC.: Pharmacognostic, Pharmacological, and Toxicological Perspective
نویسندگان
چکیده
Holarrhena antidysenterica (L.) Wall. ex A. DC. is a medicinal plant abundantly found in India. Its uses are mentioned in the classical Ayurvedic literature and by many folklore claims. The plant is also of extreme economic importance. Its seeds are mainly used as an antidiabetic remedy. All pharmacological and toxicological aspects of this plant are discussed in this review.
منابع مشابه
In vitro antioxidant activity of Holarrhena antidysenterica Wall. methanolic leaf extract
Antioxidative potential of methanolic leaf extract of Holarrhena antidysenterica was evaluated using hydroxyl radical, superoxide anion scavenging and reducing power assays. The antioxidant activity of the methanol extract increased in a concentration-dependent manner. The extract showed significant reactive oxygen species (ROS) scavenging activity in all in vitro antioxidant assays and contain...
متن کاملEffect of Methanolic Extract of Holarrhena Antidysenterica Bark against Experimentally Induced Inflammatory Bowel Disease in Rats
It has been demonstrated that Holarrhena antidysenterica Wall. (Apocynaceae) is useful as an adjunctive therapy for Inflammatory bowel disease (IBD). However, its effect on ulcerative colitis has not been investigated. In the present study, Holarrhena antidysenterica was tested for 2, 4 dinitro benzene sulfonic acid (DNBS) induced colitis, and antioxidant activity was evaluated to clarify its p...
متن کاملAntibacterial and antidiarrhoeal effects of alkaloids of Holarrhena antidysenterica WALL.
The alkaloids from the ethanolic extract of H. antidysenterica seeds were evaluated for their antibacterial activity against clinical isolates of enteropathogenic Escherichia coli (EPEC) in vitro, and their antidiarrhoeal activity on castor oil-induced diarrhoea in rats, in vivo. The plasmid DNA, whole cell lysate and outer membrane protein profile of a clinical isolate of EPEC was determined i...
متن کاملComputation of In Vivo Antidiabetic Activity of Holarrhena Antidysenterica Seeds Extracts in Streptozotocin-Induced Diabetic Rats
Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...
متن کاملExtraction Efficacy, Antibacterial Potential and Validation of Rp-hplc Coupled with Diode Array Detection in Holarrhena Pubescens
A rapid, simple, sensitive and reproducible RP-HPLC method was developed for the determination of conessine (bioactive steroidal alkaloid) in Holarrhena pubescens, a highly valued medicinal plant extensively used in pharmaceuticals. Separation was achieved on Discovery (R) RP Amide C16 Supelco column (250 μm x 4.6 μm ID) using a mobile phase of acetonitrile: water (95:5 v/v) with flow rate 0.6 ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2017